Brian is a stand-up comedian who uses observational, sarcastic, and self-deprecating humor. His performances are clean as he refrains from profanity and off-color humor. Regan’s material typically covers everyday events, such as shipping a package with UPS and a visit to an optometrist. Regan makes frequent references to childhood, including little league baseball, grade school spelling bees, and science projects. Body language and facial expressions make his stand-up act atypically physical. His clean, off-center humor has been praised by critics and contemporaries alike and Regan enjoys a fan base that crosses age groups.